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You probably know about carbohydrates, proteins, and fats in your foods, but did you know that these molecules are also inside you? These molecules, along with nucleic acids, are known as macromolecules. Macromolecules are found in all living organisms because they provide necessary functions for life. Each macromolecule has its own structure and role within the body. Some roles macromolecules provide are energy storage, structure, maintaining genetic information, insulation, and cell recognition.
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Jetzt kostenlos anmeldenYou probably know about carbohydrates, proteins, and fats in your foods, but did you know that these molecules are also inside you? These molecules, along with nucleic acids, are known as macromolecules. Macromolecules are found in all living organisms because they provide necessary functions for life. Each macromolecule has its own structure and role within the body. Some roles macromolecules provide are energy storage, structure, maintaining genetic information, insulation, and cell recognition.
The definition of macromolecules is large molecules found inside cells that help them with functions needed for organism survival. Macromolecules are found within all living organisms in the forms of carbohydrates, nucleic acids, lipids, and proteins.
Without these essential molecules, organisms would die.
The characteristics of macromolecules are made up of smaller molecules that are covalently bonded. The small molecules inside the macromolecules are known as monomers, and the macromolecules are known as polymers.
Covalent bonds are bonds formed between atoms via the sharing of at least one electron pair.
Monomers and polymers are primarily made up of carbon (C), but they can also have hydrogen (H), nitrogen (N), oxygen (O), and potentially traces of additional elements.
Micromolecules are another name for the monomers of macromolecules.
Carbohydrate micromoelcules are monosaccharides, also known as simple sugars.
Protein micromolecules are amino acids.
Lipid micromolecules are glycerol and fatty acids.
Nucleic acid monomers are nucleotides.
There are many different types of macromolecules. The four we will focus on are carbohydrates, proteins, lipids (fats) and nucleic acids.
Carbohydrates are made of hydrogen, carbon, and oxygen.
Carbohydrates can be broken down into two categories: simple carbohydrates and complex carbohydrates.
Simple carbohydrates are monosaccharides and disaccharides. Simple carbohydrates are small molecules composed of only one or two molecules of sugars.
Monosaccharides are composed of one molecule of sugar.
They are soluble in water.
Monosaccharides are building blocks (monomers) of larger molecules of carbohydrates called polysaccharides (polymers).
Examples of monosaccharides: glucose, galactose, fructose, deoxyribose, and ribose.
Complex carbohydrates are polysaccharides. Complex carbohydrates are molecules composed of a chain of sugar molecules that are longer than simple carbohydrates.
Proteins are one of the most fundamental molecules in all living organisms. Proteins are made of amino acids, and are present in every single cell in living systems, sometimes in numbers larger than a million, where they allow for various essential chemical processes, such as DNA replication. There are four different types of proteins depending on the structure of the protein itself.
These four protein structures will be discussed later.
There are two main types of lipids: triglycerides and phospholipids.
Triglycerides are lipids that include fats and oils. Fats and oils are the most common types of lipids found in living organisms. The term triglyceride comes from the fact that they have three (tri-) fatty acids attached to glycerol (glyceride). Triglycerides are entirely insoluble in water (hydrophobic).
The building blocks of triglycerides are fatty acids and glycerol. Fatty acids that build triglycerides can be saturated or unsaturated. Triglycerides composed of saturated fatty acids are fats, while those consisting of unsaturated fatty acids are oils. They help with energy storage.
Like triglycerides, phospholipids are lipids built of fatty acids and glycerol. However, phospholipids are composed of two, not three, fatty acids. Like in triglycerides, these fatty acids can be saturated and unsaturated. One of the three fatty acids that attach to glycerol is replaced with a phosphate-containing group.
The phosphate in the group is hydrophilic, meaning it interacts with water. This gives phospholipids one property that triglycerides don't have: one part of a phospholipid molecule is soluble in water. Phospholipids aid in cell recognition.
Nucleic acids store and maintain genetic information within an organism. There are two forms of nucleic acids, DNA and RNA. DNA and RNA are made up of nucleotides, the monomers for nucleic acids.
While macromolecules are found in all foods, different foods will have higher amounts of macromolecules than other foods. For example, meat would have more protein than an apple.
Examples of proteins are found in meats, legumes, and dairy products.
Examples of carbohydrates are found in foods such as fruits, vegetables, and grains.
Lipids are found in foods such as animal products, oils, and nuts.
Nucleic acids are found in all foods, but there are higher amounts in meats, seafood, and legumes.
Different macromolecules have different functions, but they all have the same goal of keeping an organism alive!
Carbohydrates are essential in all plants and animals as they provide much-needed energy, mostly in the form of glucose.
Not only are carbohydrates great energy storage molecules, but they are also essential for cell structure and cell recognition.
Proteins have a vast array of functions in living organisms. According to their general purposes, we can group them into fibrous, globular, and membrane proteins.
Fibrous proteins are structural proteins that are, as the name suggests, responsible for the firm structures of various parts of cells, tissues, and organs. They do not participate in chemical reactions but strictly operate as structural and connective units.
Globular proteins are functional proteins. They perform a much wider range of roles than fibrous proteins. They act as enzymes, carriers, hormones, receptors, etc. Essentially, globular proteins carry out metabolic functions.
Membrane proteins serve as enzymes, facilitate cell recognition, and transport the molecules during active and passive transport.
Lipids have numerous functions that are significant for all living organisms:
Energy storage (Fatty acids are used to store energy in organisms, they are saturated in animals and unsaturated in plants)
Structural components of cells (Lipids make up the cell membranes in organisms)
Cell recognition (Glycolipids aid in this process by binding to receptors on neighboring cells)
Insulation (Lipids found under the skin are able to insulate the body and maintain a constant internal temperature)
Protection (Lipids are also able to provide an extra layer of protection, for example, vital organs will have fat surrounding them to protect them from harm)
Hormone regulation (Lipids are able to help regulate and produce necessary hormones in the body such as leptin, a hormone that prevents hunger)
Depending on whether it is RNA or DNA, nucleic acids will have differing functions.
The chief function of DNA is to store genetic information in structures called chromosomes. In eukaryotic cells, DNA can be found in the nucleus, the mitochondria, and the chloroplast (in plants only). Meanwhile, prokaryotes carry DNA in the nucleoid, which is a region in the cytoplasm, and plasmids.
Plasmids are small double-stranded DNA molecules typically found in organisms such as bacteria. Plasmids aid in the transport of genetic material to organisms.
RNA transfers genetic information from the DNA found in the nucleus to the ribosomes, specialized organelles comprised of RNA and proteins. The ribosomes are especially important as translation (the final stage of protein synthesis) occurs here. There are different types of RNA, such as messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA), each with its specific function.
Macromolecule structures play a vital role in their function. Here we explore the various macromolecule structures of each type of macromolecule.
Carbohydrates are composed of molecules of simple sugars - saccharides. Therefore, a single monomer of carbohydrates is called a monosaccharide. Mono- means 'one,' and -sacchar means 'sugar.' Monosaccharides can be represented by their linear or ring structures. Disaccharides will have two rings and polysaccharides will have multiple.
The basic unit in the protein structure is an amino acid. Amino acids are joined together by covalent peptide bonds, which form polymers called polypeptides. Polypeptides are then combined to form proteins. Therefore, you can conclude that proteins are polymers composed of amino acids and monomers.
Amino acids are organic compounds composed of five parts:
There are 20 amino acids naturally found in proteins with a different R group.
Also, based on the sequence of amino acids and the complexity of the structures, we can differentiate four structures of proteins: primary, secondary, tertiary, and quaternary.
The primary structure is the sequence of amino acids in a polypeptide chain. The secondary structure refers to the polypeptide chain from the primary structure folding in a certain way in specific and small sections of the protein. When the secondary structure of proteins starts to fold further to create more complex structures in 3D, the tertiary structure is formed. The quaternary structure is the most complex of them all. It forms when multiple polypeptide chains, folded in their specific way, are bonded with the same chemical bonds.
Fig. 2. The four protein structures.
Lipids are composed of glycerol and fatty acids. The two are bonded with covalent bonds during condensation. The covalent bond that forms between glycerol and fatty acids is called the ester bond. Triglycerides are lipids with one glycerol and three fatty acids, while phospholipids have one glycerol, a phosphate group, and two fatty acids instead of three.
Depending on whether it is DNA or RNA, nucleic acids can have different structures.
The DNA molecule is an anti-parallel double helix formed of two polynucleotide strands. It is anti-parallel, as the DNA strands run in opposite directions to each other. The two polynucleotide strands are joined together by hydrogen bonds between complementary base pairs, which we will explore later. The DNA molecule is also described as having a deoxyribose-phosphate backbone - some textbooks may also call this a sugar-phosphate backbone.
The RNA molecule is a little different to DNA in that it is made of only one polynucleotide which is shorter than DNA. This helps it carry out one of its primary functions, which is to transfer genetic information from the nucleus to the ribosomes - the nucleus contains pores that mRNA can pass through due to its small size, unlike DNA, a larger molecule. Below in Figure 4, you can visually see how DNA and RNA differ from each other, both in size and the number of polynucleotide strands.
Fig. 4. DNA vs RNA structure.
The four major biological macromolecules are carbohydrates, proteins, lipids, and nucleic acids.
Examples of macromolecules are amino acids (proteins), nucleotides (nucleic acids), fatty acids (lipids), and monosaccharides (carbohydrates).
Macromolecules are large molecules inside cells that help them with functions necessary for life.
Depending on the type of macromolecule, they have different functions within living organisms. They can aid as fuel, provide structural support, and maintain genetic information.
Macromolecules are also called polymers because they are made up of many smaller units (this is where the prefix 'poly' comes from).
Macromolecules are large molecules that consist of covalent bonds and smaller repeating units known as monomers.
While all macromolecules are essential, the most important are nucleic acids because, without them, there would not be a way to form the other macromolecules.
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SIGNUP SIGNUPFlashcards in Macromolecules15
Start learningMacromolecules are found in all living organisms.
True
Which is the most important macromolecule?
Nucleic acids
What are macromolecules?
Macromolecules are large molecules found inside cells that help them with functions necessary for life.
What are the two types of carbohydrates?
Simple and complex
What are proteins made up of?
Amino acids
What is the purpose of carbohydrates?
Energy storage, cell recognition, and structure
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