Open in App
Log In Start studying!

Select your language

Suggested languages for you:
StudySmarter - The all-in-one study app.
4.8 • +11k Ratings
More than 3 Million Downloads
Free
|
|
Nucleic Acids

Nucleic acids are the key macromolecules of life. They are polymers made of smaller monomers called nucleotides, which undergo condensation reactionsThe two types of nucleic acids you'll learn about are deoxyribonucleic acid, or DNA, and ribonucleic acid, or RNA. Both DNA and RNA are essential in cellular processes and development. All living things - both eukaryotic and prokaryotic    - contain nucleic acids, including animals, plants and bacteriaEven viruses, which are considered non-living entities, contain nucleic acids as you can see in the diagram below.

Content verified by subject matter experts
Free StudySmarter App with over 20 million students
Mockup Schule

Explore our app and discover over 50 million learning materials for free.

Nucleic Acids

Illustration

Lerne mit deinen Freunden und bleibe auf dem richtigen Kurs mit deinen persönlichen Lernstatistiken

Jetzt kostenlos anmelden

Nie wieder prokastinieren mit unseren Lernerinnerungen.

Jetzt kostenlos anmelden
Illustration

Nucleic acids are the key macromolecules of life. They are polymers made of smaller monomers called nucleotides, which undergo condensation reactions. The two types of nucleic acids you'll learn about are deoxyribonucleic acid, or DNA, and ribonucleic acid, or RNA. Both DNA and RNA are essential in cellular processes and development. All living things - both eukaryotic and prokaryotic - contain nucleic acids, including animals, plants and bacteria. Even viruses, which are considered non-living entities, contain nucleic acids as you can see in the diagram below.

Nucleic acids, location of DNA, StudySmarterFig. 1 - DNA is located in a eukaryotic cell (left) and a virus (right)

DNA and RNA are composed of three common components: a phosphate group, a pentose sugar and an organic nitrogenous base. The combination of these components, called the base sequence (shown below), holds all the genetic information needed for all life.

Nucleic acids, DNA base sequence, StudySmarterFig. 2 - DNA base sequence

Why are nucleic acids important?

Nucleic acids are amazing molecules that contain the genetic instructions to make our cellular components. They are present in every cell (except mature erythrocytes) to direct the functioning of each cell and its functions.

DNA is a remarkable macromolecule found in both eukaryotic and prokaryotic cells that holds all the information needed to create proteins. The base sequence of DNA holds this code. This same DNA is passed down to offspring, so subsequent generations possess the ability to create these essential proteins. This means that DNA plays a major role in the continuity of life as it is the blueprint for organizational development.

Genetic information flows from DNA to RNA. RNA is involved in the transfer of the information stored in DNA and the 'reading' of the base sequence, both of which are processes in protein synthesis. This nucleic acid type is present in both transcription and translation, so it is needed in every step of protein synthesis.

This is highly important because, without RNA, proteins cannot be synthesized. There are different types of RNA that you will come across: messenger RNA (mRNA), transport RNA (tRNA) and ribosomal RNA (rRNA).

Nucleic Acids - Key takeaways

  • Nucleic acids are the essential macromolecules responsible for the storage and transfer of genetic material.
  • The two types of nucleic acids, DNA and RNA, share three common structural components: a phosphate group, a pentose sugar and a nitrogenous base.
  • DNA holds all the genetic information in the form of base sequences that code for proteins.
  • RNA facilitates the transcription and translation of the DNA base sequence in protein synthesis.
  • There are three different types of RNA, each with different functions: mRNA, tRNA and rRNA.

Frequently Asked Questions about Nucleic Acids

Nucleic acids are macromolecules found in all living cells, like plants, and non-living entities, like viruses. DNA is the nucleic acid responsible for storing all the genetic information, while RNA facilitates the transfer of this genetic material to protein synthesis organelles.

There are two types of nucleic acids: deoxyribonucleic acid, DNA and ribonucleic acid, RNA. There are also different types of RNA: messenger, transport and ribosomal RNA.

Viruses contain nucleic acids, either DNA, RNA or even both. Even though viruses are not classified as 'living cells', they still require nucleic acids to store the code for their viral proteins.

Nucleic acids are organic molecules as they contain carbon, hydrogen and are found in living cells.

Nucleic acids are composed of monomeric units called nucleotides. In animals, these nucleotides are primarily made in the liver or obtained from our diet. In other organisms like plants and bacteria, metabolic pathways use available nutrients to synthesize nucleotides.

Final Nucleic Acids Quiz

Nucleic Acids Quiz - Teste dein Wissen

Question

Both DNA and RNA are _____ acids.

Show answer

Answer

Nucleic.

Show question

Question

Compare the functions of DNA and RNA.


Show answer

Answer

DNA stores genetic information while RNA transfers this genetic information for protein synthesis.

Show question

Question

Where is DNA found in the cells of eukaryotes and prokaryotes?


Show answer

Answer

In eukaryotes, DNA is in the nucleus, mitochondria and chloroplast (in plants). 


In prokaryotes, DNA is in the nucleoid and plasmids.

Show question

Question

Where is RNA found in the cells of eukaryotes and prokaryotes?


Show answer

Answer

In eukaryotes, RNA is in the nucleolus and ribosomes. 


In prokaryotes, RNA is in the nucleoid, plasmids and ribosomes.

Show question

Question

Identify the three different types of RNA.


Show answer

Answer

Messenger RNA (mRNA), transfer RNA (tRNA) and ribosomes RNA (rRNA).

Show question

Question

What nitrogenous bases can DNA nucleotides have?


Show answer

Answer

Adenine, thymine, cytosine or guanine.

Show question

Question

What nitrogenous bases can RNA nucleotides have?


Show answer

Answer

Adenine, uracil, cytosine and guanine.

Show question

Question

Identify the pyrimidine and purine bases. 


Show answer

Answer

The pyrimidine bases are cytosine, uracil and thymine. 


The purine bases are adenine and guanine.

Show question

Question

DNA contains the _____ pentose sugar while RNA contains the _____ pentose sugar. 


Show answer

Answer

Deoxyribose. 

Ribose.

Show question

Question

________ reactions form polynucleotides while _____ reactions break polynucleotides. 

Show answer

Answer

Condensation. 

Hydrolysis.

Show question

Question

What are phosphodiester bonds and how are they formed?


Show answer

Answer

Phosphodiester bonds link nucleotides together. They are formed between the phosphate group of one nucleotide and the hydroxyl group at the 3 'pentose sugar of another nucleotide.

Show question

Question

Compare the structure of a DNA and RNA molecule. 


Show answer

Answer

DNA is an anti-parallel double helix made of 2 polynucleotide strands while RNA is a single-stranded molecule made of 1 polynucleotide strand.

Show question

Question

What is complementary base pairing? 


Show answer

Answer

Complementary base pairing is the joining of a pyrimidine base to a purine base via hydrogen bonds.

Show question

Question

In complementary base pairing, how many hydrogen bonds are formed between the base pairs?


Show answer

Answer

Adenine forms 2 hydrogen bonds with thymine in DNA, or uracil in RNA. 


Cytosine forms three hydrogen bonds with guanine.

Show question

Question

DNA and RNA are polynucleotides. The monomers that make up these polynucleotides are called _____.

Show answer

Answer

Nucleotides.

Show question

Question

When does DNA replication happen?


Show answer

Answer

During the S phase of the cell cycle, before cell division. 


Show question

Question

Where does DNA replication occur in a cell?


Show answer

Answer

In the nucleus, in eukaryotic cells.

Show question

Question

After one round of DNA replication, what does the semiconservative model state?


Show answer

Answer

The new DNA molecule contains one original strand of DNA and one new strand of DNA.

Show question

Question

Why is DNA replication important?


Show answer

Answer

DNA replication ensures that the daughter cells contain the correct amount of DNA. It is also required for cell division.

Show question

Question

What is the function of DNA helicase?

Show answer

Answer

DNA helicase breaks the hydrogen bonds between complementary base pairs. This unzips the DNA double helix to expose the DNA bases.

Show question

Question

What is the function of DNA polymerase?


Show answer

Answer

DNA polymerase catalyses the formation of phosphodiester bonds between adjacent nucleotides.

Show question

Question

What is the function of DNA ligase?


Show answer

Answer

DNA ligase catalyses the formation of phosphodiester bonds between Okazaki fragments in discontinuous replication.

Show question

Question

In what direction does the new DNA strand extend?


Show answer

Answer

The 5 'to 3' direction.

Show question

Question

The _____ strand undergoes continuous replication as it is being continuously synthesized by DNA polymerase.


Show answer

Answer

Leading.

Show question

Question

The lagging strand undergoes _______ replication as Okazaki fragments are made. 


Show answer

Answer

Discontinuous.

Show question

Question

The enzyme ___ _______ joins together Okazaki fragments by catalysing the formation of what bond?


Show answer

Answer

DNA ligase. 


Phosphodiester bonds.

Show question

Question

What model did Meselson and Stahl prove correct in the 1950s?


Show answer

Answer

The semiconservative model of DNA replication.

Show question

Question

Describe the replication fork.


Show answer

Answer

The replication fork is a Y-shaped structure that forms due to the unzipping action of DNA helicase. Each branch of the fork is an exposed strand of DNA.

Show question

Question

Which end of the original DNA molecule does DNA polymerase initially bind to?


Show answer

Answer

The 3 'end.

Show question

Question

Both ___ _______ and ___ _______ are enzymes involved in DNA replication that form phosphodiester bonds. 


Show answer

Answer

DNA polymerase. 


DNA ligase.

Show question

Question

What kind of macromolecules are nucleic acids?

Show answer

Answer

Polymers made of monomers called nucleotides.

Show question

Question

What are the two types of nucleic acids?

Show answer

Answer

DNA and RNA.

Show question

Question

What are the components of both nucleic acid types?


Show answer

Answer

A phosphate group, a pentose sugar and a nitrogenous base.

Show question

Question

What reaction is needed to synthesize nucleic acid?


Show answer

Answer

Condensation reactions between nucleotides.

Show question

Question

What kind of cells contain nucleic acids?


Show answer

Answer

 Eukaryotic and prokaryotic cells, such as animals, plants and bacteria. Also, non-living entities such as viruses.

Show question

Question

What is the base sequence in DNA?


Show answer

Answer

The combination of DNA nucleotides that encode proteins.

Show question

Question

What process requires RNA?

Show answer

Answer

Protein synthesis (transcription and translation).

Show question

Question

What are the different types of RNA?


Show answer

Answer

Messenger RNA (mRNA), transport RNA (tRNA) and ribosomal RNA (rRNA).

Show question

Question

What cells do not contain nucleic acids?


Show answer

Answer

Mature erythrocytes.

Show question

Question

DNA is the abbreviation for ___________ ______.


Show answer

Answer

Deoxyribonucleic acid.

Show question

Question

RNA is the abbreviation for ________ _____.


Show answer

Answer

Ribonucleic acid.

Show question

Flashcards in Nucleic Acids41

Start learning

Both DNA and RNA are _____ acids.

Nucleic.

Compare the functions of DNA and RNA.


DNA stores genetic information while RNA transfers this genetic information for protein synthesis.

Where is DNA found in the cells of eukaryotes and prokaryotes?


In eukaryotes, DNA is in the nucleus, mitochondria and chloroplast (in plants). 


In prokaryotes, DNA is in the nucleoid and plasmids.

Where is RNA found in the cells of eukaryotes and prokaryotes?


In eukaryotes, RNA is in the nucleolus and ribosomes. 


In prokaryotes, RNA is in the nucleoid, plasmids and ribosomes.

Identify the three different types of RNA.


Messenger RNA (mRNA), transfer RNA (tRNA) and ribosomes RNA (rRNA).

What nitrogenous bases can DNA nucleotides have?


Adenine, thymine, cytosine or guanine.

Join over 22 million students in learning with our StudySmarter App

The first learning app that truly has everything you need to ace your exams in one place

  • Flashcards & Quizzes
  • AI Study Assistant
  • Study Planner
  • Mock-Exams
  • Smart Note-Taking
Join over 22 million students in learning with our StudySmarter App Join over 22 million students in learning with our StudySmarter App

Sign up to highlight and take notes. It’s 100% free.

Start learning with StudySmarter, the only learning app you need.

Sign up now for free
Illustration